Regenerative Medicine Archives - Apple Health and Wellness

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What is HA Therapy?

Hyaluronic Acid (HA) therapy, also known as viscosupplementation, is a regenerative and preventative focused treatment plan for individuals suffering from osteoarthritis of the knee and/or ankle.

Who Can Benefit from HA Therapy

You may be eligible for this procedure if you have have exhausted standard treatment options, such as weight control, steroid injections, and medication, and want to avoid invasive surgical procedures.

Osteoarthritis is a “drying” problem of the joints, and hyaluronic acid therapy “replenish the oil” in the knee or ankle to teach your body’s fluid-producing cells how to start producing new cells again.

According to a study of 182,000 people during the time leading up to their total knee replacement procedures (TKR) with and without HA therapy, the patients that had HA therapy averaged 17 months until a TKR, rather than 8.5 months for a patient who did not have HA therapy. The study also found that with subsequent injections, this delay to surgery increased even more.

Our Approach to HA Therapy

At Apple Healthcare Group, our HA treatment plan involves a four-pronged approach that includes: (1) evaluation and proper diagnosis, (2) Supartz injection, (3) physical/exercise therapy, and (4) specialized bracing (if needed).

Step 1: Evaluation and Proper Diagnosis

Osteoarthritis involves the degeneration of joints and surrounding tissue area, you may be experiencing symptoms such as pain, stiffness, and decreased movement.. If you have been suffering from this condition for a while, you have probably tried many of the standard treatments options available, but still are not finding relief.

When you come to Apple Healthcare Group, we will conduct a thorough evaluation of your condition and recommend a proper diagnosis based on your immediate and long-term needs. One of these options may be HA therapy if you are a good candidate for the procedure. Other regenerative focused treatment options include Platelet Rich Plasma (PRP) or stem cell therapy.

Step 2: Supartz Injection

Not all viscosupplementation injection options are created equal. Supartz is a pure, natural form of hyaluronic acid and is not considered a medical drug. It is the most effective of all viscosupplements due to its long lasting patient results. When injected, this acid cushions and lubricates your joints and has very few side effects and interactions. 

For the injection, our medical specialists are guided by fluoroscopy to maintain the highest degree of accuracy for the injection location. According to the American Journal of Sports Medicine, imaging strategies like this are 99 percent accurate versus non-imaging techniques that are only 75 percent accurate. For this reason, at Apple Healthcare group, we never guess, we always see before we start the procedure.

Step 3: Physical/Exercise Therapy

Some patients will experience additional improvements from physical or exercise therapy in addition to their HA injections. This treatment plan will involve a series of stretches, exercises, and challenges that will help lessen stiffness and pain in the knee or ankle area. Our skilled physical therapy team will strive to help you boost your optimal health goals in addition to the HA therapy you are already receiving.

Step 4: Specialized Bracing

Depending on your needs, we may recommend specialized bracing to maximize your potential of finding lasting relief. This bracing technique will reduce pressure throughout your knee, align it, and hopefully restore strength to the area. 

Our braces are considered “Durable Medical Equipment” (DME), and are able to be fitted to your unique needs. They are also longer-lasting and of higher-quality than off-the-shelf braces that you can buy in retail stores.

Think HA therapy might be right for you? Want to learn more? Schedule an evaluation today, by calling us at(865) 769-9685. Follow us on Facebook, Twitter, or Instagram, or subscribe to our Newsletter for more information during Regenerative Medicine Month.


Suffering from chronic pain in your joints, muscles, tendons, lower back, or neck? Severely strained or pulled a muscle due to improper or overuse? While mild to moderate strains and minor aches and pains can be treated at home, more severe injuries and conditions require additional medical attention.

Whether you’re suffering from Achilles tendinitis or the negative results of numerous high-impact exercise routines, your pain may significantly limit your movement and affect your daily life. Though the body typically works hard to heal itself after tissue damage, the process can be lengthy and not heal properly. For example, your damaged tissue may not be replaced correctly, which could lead to chronic pain and muscle or joint weakness.

If you’re continually suffering from soreness, muscle spasms, swelling, stiffness, or experiencing a limited range of movement due to a muscle or joint injury, it might be time to seek out prolotherapy to find long-lasting relief.

What Is Prolotherapy?

Many patients seeking out non-surgical options for their musculoskeletal pain turn to a regenerative treatment plan, prolotherapy, for pain management. Also referred to as proliferative therapy, prolotherapy helps treat a range of chronic and serious conditions, such as injuries to the tendons, joints, or muscles and chronic elbow or lower back issues.

When to See Us

For moderate strains or minor pain, you should be able to find relief from a variety of home treatment options. Meanwhile, if you are dealing with a serious injury or chronic condition, now is the time to seek out help from a medical professional.

Don’t wait until you can’t move your arms or legs, or are in unbelievable pain to seek out treatment options and call Apple Healthcare Group to learn more about prolotherapy today.

How We Treat This Condition

Once we conduct a thorough examination and conclude that prolotherapy is the right treatment plan for your condition, a skilled medical doctor will use a long, thin needle to inject a solution to several points around your target pain area. This solution usually contains a local anesthetic and a concentration of dextrose. The precise dosage will depend on the affected region of the body and severity of the condition.

When injected, the solution will intentionally cause irritation, which will force your body to reset and restart the healing process through an increase of the blood supply and stimulation of tissue growth. To ensure patient safety and procedural accuracy, your doctor will perform the injection with ultrasound or fluoroscopic guidance. Most appointments take around 30 minutes, and many patients are able to resume their normal level of activity very soon after the procedure.

How Soon Will You Experience Relief?

As a result of this treatment, your joints, tendons, muscles, and ligaments should be strengthened and stabilized, leading to a reduction in the severity of your pain. It is a safe and ideal option for anyone dealing with chronic or severe pain and looking for a way to avoid invasive surgery.

While some patients start feeling better soon after the treatment, others return for several sessions over the course of three to six months. Other patients combine prolotherapy with physical or occupational therapy to find additional relief.

Call Us Today

Need relief from your muscle, joint, or tendon injury? Tired of suffering from chronic pain in your neck, back, or elbow? Call us at (865) 769-9685. Follow us on Facebook, Twitter, or Instagram, or subscribe to our Newsletter for more information during Regenerative Medicine Month.



Are you experiencing intense pain from Osteoarthritis (OA) in your knees, ankles, wrists, elbows, or shoulders? Maybe your joints are feeling more stiff and tender, making it difficult to get around?

While OA isn’t curable, you can turn to stem cell and regenerative therapy to find relief. Apple Healthcare Group is one of a growing number of clinics across the country to offer this breakthrough treatment method for people suffering from OA.

So how do stem cells provide relief from your OA? Well, as stem cells are the building blocks of the body, your body has been healing itself with stem cells for your entire life. Most of the time, you can rely on these cells to see you through the healing process. The process becomes more complicated as we age, which is why stem cell and regenerative therapy is so revolutionary.


As mentioned previously, OA is a generative form of arthritis that involves degradation of the joints that may include the subchondral bone and articular cartilage. Anytime bone surfaces become less cushioned and protected by cartilage, the bone becomes exposed and more prone to damage.

Common symptoms include joint pain, locking, stiffness, discomfort, and an effusion. Many people report feeling less mobile as the condition progresses without treatment. If you are experiencing these symptoms with increasing severity, it may be time to seek out additional medical help.

When to See Us

If you are suffering from OA, you should seek out professional help to find some level of relief through a targeted treatment plan. As Apple Healthcare Group is one of the few clinics to offer stem cell and regenerative therapy to patients suffering from OA, we should be first one your list as you are weighing your potential treatment options.

Our regenerative medicine treatment uses mesenchymal growth factors and stem cells from umbilical cord matrix to help the body heal faster, regenerate tissue, and decrease pain allowing us to see better and faster results.

How We Treat Osteoarthritis 

Once you come into the office, your treatment will likely focus on Platelet Rich Plasma (PRP) and an injection of mesenchymal stems cells (MSC) and growth factors. PRP is a concentration of your own platelets with high amounts of healing growth factors. While these treatments may be used independently, we have seen the combination of the two produces better clinical outcomes.

The medical staff will handle the injections guided by fluoroscopy, which is a unique type of medical imaging. Only a few clinics use this method to guide their injections.

For severe cases, some patients elect for a second round of PRP, which will be administered three months after the initial treatment to further increase the chances of positive medical outcomes.

How Soon Will You Experience Relief?

Most patients start feeling significantly better within a month or two after their treatment. However, continued repair and improvement is still common for the first three to six months after the procedure. Some evidence event suggests the treatment promotes rebuilding for up to a year.

Like many other innovative procedures, the results are not entirely guaranteed. With this in mind, this procedure is not for everyone, which is why a thorough evaluation and discussion with your healthcare provider is essential.


Call Us Today

Think regenerative medicine therapy might be right for you? To schedule an evaluation today , call us at(865) 769-9685. Follow us on Facebook, Twitter, or Instagram, or subscribe to our Newsletter for more information during Regenerative Medicine Month.


Experiencing long-term pain and sensitivity in one or both of your knees? Struggling to get up or down stairs? Are everyday tasks becoming more difficult to accomplish because of constant pain if your knees?

You’re not alone: Thousands of Americans suffer from chronic knee pain just like you. While age is a major factor leading to knee pain, it is a condition that can affect people of all ages and for a variety of reasons.

Chronic knee problems are different than short-term knee injuries, as the latter condition will go away with treatment and is usually only caused by one accident or injury. Meanwhile, chronic knee pain usually is caused by numerous conditions or illnesses and doesn’t always go away with treatment.

Some of the most common causes of chronic knee pain include osteoarthritis, bursitis, tendinitis, meniscus tear, and rheumatoid arthritis. Commonly referred to as “wear-and-tear arthritis,” osteoarthritis in the knee is one of the leading causes of disability in the U.S.

Dealing with Knee Pain Caused by Osteoarthritis

Chronic knee pain affects everyone differently. However, if you are suffering from osteoarthritis or a similar condition, you likely are experiencing stiffness, swelling, shooting pain, dull burning, and the decreased ability to move. Other symptoms may include popping or crunching noises, inability to straighten the knee, weakness, and redness and warmth to the touch.

As there is no cure for arthritis and osteoarthritis occurs when the cushioning between joints wears away, it is important not to avoid the symptoms and seek out medical help before your condition worsens. There might not be a cure, but it is possible to receive some relief from your chronic pain.

While you can take anti-inflammatory drugs, ice your knees, and avoid over exerting your joints to minimize discomfort, you should always seek out professional medical advice when it comes to chronic knee pain. Don’t try to treat this condition at home.

In regards to prevention, it’s important to note that individuals who are overweight or obese are at a greater risk for developing chronic knees problems. To reduce your chances of being affected by this condition, maintain a healthy weight through low-impact exercise and healthy eating.

Other factors that contribute to chronic knee pain include age, previous traumas or injury, and athletic activity. While you cannot avoid natural aging or accidental injuries, be smart about your exercise routine and participate in exercises that promote flexibility and strength building,

When to See Us

Please call your doctor if you suspect you may be developing osteoarthritis and cannot bear weight on your knee, have noticeably knee swelling, cannot extend your leg at the knee, or if your knee feels unstable or unusually weak.

Get serious about find a lasting solution to your knee problems. If you are suffering from chronic knee pain, you cannot experience relief and start to recover until you receive a proper diagnosis and treatment plan. For this reason, contact a specialist at the Apple Healthcare Group office to set up a knee evaluation today!

Regenerative Treatment Options

If you are in the early stages of arthritis of the knee, your condition will be treated with nonsurgical and noninvasive methods, which may include physical therapy, weight loss, pain relievers, and changes in activity level.  

Another common and highly effective treatment method is viscosupplementation, where a medical professional will inject a gel-like fluid called hyaluronic acid into the knee joint. This acid is naturally occurring in the fluid surrounding your joints, so it will act as a lubricant to allow your bones to move from smoothly and with less pain. Osteoarthritis causes lower levels of hyaluronic acid in the joints, so replacing this fluid may promote more knee mobility and less pain.

Chronic knee pain is not something you should live with! Come see us today to seek relief and improve your quality of life. To make your appointment today, call us at(865) 769-9685. Follow us on Facebook, Twitter, or Instagram, or subscribe to our Newsletter for more information during Regenerative Medicine Month.

Western Ave. / I-640

4307 Ball Camp Pike
Knoxville, TN 37921
Office: (865) 524-1234
Fax: (865) 524-2169

Monday: 8am - 5:30pm
Tuesday: 7am - 5:30pm
Wednesday: 7am - 11:30am
Thursday: 7am - 5:30pm
Friday: 7am - 5:30pm
Saturday: 8am - 11am
Sunday: Closed

Cedar Bluff

312 Prosperity Drive
Suite 101
Knoxville, TN 37923
Office: (865) 691-3155
Fax: (865) 694-8093

Monday: 8am - 5:30pm
Tuesday: 7am - 5:30pm
Wednesday: 2pm - 5:30pm
Thursday: 8am - 5:30pm
Friday: 7am - 5:30pm 312 Prosperity Drive
Suite 101
Knoxville, TN 37923
Office: (865) 691-3155
Fax: (865) 694-8093

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